Evaluation of the effectivity of some organic extracts of Aloe vera against some Pathogeneic bacteria
karbala journal of pharmaceutical sciences,
2018, Volume 9, Issue 14, Pages 42-49
AbstractThe aqueous, ethanol, chloroform , and acetone extracts of Aloe vera cortex leave were studied for their antimicrobial activity against two Gram-negative bacteria ( Escherichia coli and Klebsiella pneumonia ) and Gram-positive bacteria (Staphylococcus aureus) using agar well diffusion method. The extracts revealed different levels of antimicrobial activity against the tested bacterial pathogens. St .aureus was very sensitive to all types of extracts represent by a higher inhibition zone as (35.51mm) for acetone, (6.83 mm) for ethanol and (5.60 mm) for aqueous extract. On the other hand, chloroform extract showed lowered activity against Escherichia coli only and no activity against other bacteria were found. Used antibiotics against all bacteria compare with the best organic solvent which was acetone extract against all bacteria. It gave a better minimum inhibitory concentration (MIC) which was (12.5 mg/ml), (50 mgml),(25 mg/ml) against Escherichia coli, staphylococcus aureus and klebsiella pneumonia, respectively. The results showed that the best organic solvent for Aloe vera which revealed a higher antibacterial activity was acetone extraacts.
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