The analgesic effect of Local Passiflora, Cinnamon and Chamomile plant ethanol extract in Swiss albino mice
karbala journal of pharmaceutical sciences,
2017, Volume 8, Issue 12, Pages 109-119
AbstractThe study was performed to investigate the analgesic effect of the ethanol extracts of Passiflora, Cinnamon and chamomile in Swiss albino mice. Forty Swiss albino mice, and were divided into 5 groups (8 animals per each group). Analgesic activity of the plants was evaluated by using acetic acid induced writhing test, hot plate test and heat conduction test in albino mice. The study revealed that the dose (33 mg/kg) of Passiflora ethanolic extract produced (12 ±1.309) in heat conduction test (9.1250 ±1.246 sec.) in hot plate test and (7.875±1.246 stretch in 15 min.) in writhing test. The dose (8 g/kg) of cinnamon oil produced (10.875±1.246 sec.) in heat conduction test (10.25 ±1.035 sec) using hot plate test and (7±1.069 stretch in 15 min) in writhing test. The dose (13 g/kg) of chamomile oil produced (12±1.069 sec.) in heat conduction test (12.5±1.603) in hot plate test and (6.125±1.246 stretch in 15 min) in writhing test. All three plants showed analgesic effect. The strongest effect was shown by chamomile then cinnamon and last comes passiflora showing the weakest analgesic among them.
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