ISSN: 7027-2221


Preparation and characterization of some new heterocyclic compounds with evaluating of its biological activity

Ibtisam K. Jassim; Suraa Reaad; Suhad Kh.Shubber; Wissam K. Jassim

karbala journal of pharmaceutical sciences, Volume 5, Issue 7, Pages 12-20

New compounds of 2-amino 6-bromo benzothiazole [2], 2-( substituted benzylidene)-6 -bromobenzothiazole [3a-e], 2-( p-N,N-dimethylamino phenyl)- 2-yl)-tetrazolo)-6-bromobenzothiazole[4],- 2-(p-N,N-dimethylaminophenyl)-)– (4'-oxo-1̀,3̀-thiazolidin-2-yl)6-bromobenzothiazole[5], 2-(p-N,N-dimethylaminophenyl)-2-yl)– 2,3-dihydro-1,3-oxazpine-4,7-dione)-6-bromobenzothiazole[6], -2-( p-N,N-dimethylamino phenyl)- 2-yl) 2,3-dihydro-1,3-oxazpine-4,7-dione)-6-bromobenzothiazole[7], and 2-( p-N,N-dimethylamino phenyl) imidazolidine-4-one)- 6-bromo benzothiazole[8] have been synthesized. The structures of these compounds were identified by FT-IR,H-NMR,Uv spectra and checked by TLC. Some of these compounds were tested against bacteria (Escherchia coli and Staphococcus aureus ).