ISSN: 7027-2221

Keywords : diabetes mellitus


Erectile Dysfunction in Diabetic Patients in the Holy Kerbala/Iraq in 2018

karbala journal of pharmaceutical sciences, Volume 9, Issue 15, Pages 1-10

Background
Erectile dysfunction affects more than 50% of diabetic patients and results in miserable
couple’s life, especially for young adults. Possible predictors are proper therapy and
patient’s compliance with treatment, in addition to the warning signs and symptoms of
sensory neuron and motor deficits. Therefore, this study was conducted to determine the
prevalence of Erectile dysfunction and its predictors among diabetic patients in Kerbala.
Material and methods
The study included a convenient sample of 61 patients with diabetes mellitus type I and II.
They were chosen through a systematic sampling among patients at the diabetes mellitus
clinic at Al Hussein Teaching Hospital in Holy Kerbala /Iraq in 2018. All participants
were interviewed using standard questionnaire. Analysis of data used descriptive and
analytic tools including t-test, chi-square test, logistic regression and structural Equation
modeling through the statistical Package of social sciences and Amos and Excel software
at a significance level of

Keywords

diabetes mellitus
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erectile dysfunction
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Autonomic changes
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sensory and motor changes
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glycemic control.

Activity assay of plasma fibrinogen in patients with diabetes.

Mohammed Shnain Ali

karbala journal of pharmaceutical sciences, Volume 4, Issue 6, Pages 127-131

Thrombosis secondary to atherosclerosis or hypercoagulability state in diabetes mellitus may be the cause of death in many patients. Patients with diabetes mellitus (n=28, 16 males and 12 females), together with 28 age and sex matched healthy individuals (as controls), were studied after their consent. For each individual (patients and controls), following medical history,
4 ml of venous blood sample was obtained and investigated for HbA1c level, fibrinogen level by doing Claus technique and blood sugar estimation. Hyperfibrinogenaemia in patients with diabetes mellitus (mean plasma fibrinogen 6.8±1.1) is statistically significant (P< 0.05) as compared to control (mean plasma fibrinogen 3.3±1.3). Plasma fibrinogen level is high in patients with diabetes mellitus, suggesting that plasma fibrinogen can contribute to vascular diseases in patients with diabetes mellitus like vascular thrombosis.

Is There Any Association Between Type 2 Diabetes Mellitus and Biochemical Evidence of Vitamin D Deficiency?

Riyadh Mustafa Murtadha

karbala journal of pharmaceutical sciences, Volume 4, Issue 6, Pages 147-152

Background: Type 2 Diabetes Mellitus is a major public health problem, known to be multifactorial in origin. Over the last years, a number of observational studies have suggested an association between type 2 diabetes mellitus and vitamin D deficiency.
Objective: To identify any association between type 2 diabetes mellitus and biochemical evidence of vitamin D deficiency in our population.
Methods: This study was conducted at outpatient clinic in Karbala throughout the year 2011, with a cross-sectional design. The populations were patients with type 2 diabetes mellitus and non-diabetic subjects, who visited the clinic for treatment; all of them had normal renal function. Data collected including characteristics, such as age, sex & body mass index; and the laboratory data such as serum level of calcium, phosphorus, albumin and alkaline phosphatase. Statistical analysis was done by using Chi-Square test and multivariate analysis.
Results: A total number of 64 subjects (Age 45-75 years; 67% female); of them, 32 subjects with Type 2 diabetes mellitus, and 32 subjects without diabetes mellitus. The biochemical evidence of vitamin D deficiency was found in 22% (7 out of 32) of diabetic patients, while it was in 25% (8 out of 32) of non-diabetic subjects. So, there was no statistical difference between the two groups. Moreover, among diabetics, there was no effect of vitamin D deficiency on blood sugar control by measuring HbA1C level.
Conclusions: The association between type 2 diabetes mellitus and biochemical evidence of vitamin D deficiency cannot be proven statistically in this study.