ISSN: 7027-2221

Keywords : Autism

Effect of nystatin drug on the level of immunoglobulin's in children with autism

A. F; Alhaidary; Mousa; R.F

karbala journal of pharmaceutical sciences, Volume 5, Issue 8, Pages 47-55

Autism spectrum disorders (ASD) are a group of heterogeneous, behaviorally defined disorders characterized by disturbances in both verbal and non-verbal communication, language, imagination, and social interaction, often with repetitive and stereotyped behavior . The aim of this study is to achieve serum level of immunoglobulin IgE near normal value in children with autism after nystatin administration . This study was performed on 30 child with autism spectrum disorders (ASD) that are go to psychiatric clinic at Al – Hussain teaching Hospital/kerbala –Iraq. The study revealed significant different on a level of immunoglobulins in autism spectrum disorders as compared with control group .This study indicate the reduction in level of IgG,IgA,IgM,IgE in autism child when compared with the same immunoglobulins in control group ,also this study showed an increase in the level of IgE level (p=0.01) in patient with autism and discus the relationship between it and Candida Albecan fungi for this reason the study treated this fungi by using anti fungi drug (nystatin) ,that lead to reduce the level of IgE in patient to be near the value in control group . The last result improve behavior of autism after treatment with nystatin .