ISSN: 7027-2221

Keywords : Methicillin Resistance Staphylococcus aureus

Antibiotic Resistance Patterns of Community Acquired Methicillin Resistance Staphylococcus aureus(CA-MRSA) in Al-Hilla/ Iraq

Huda H. Al-Hassnawi; Alaa H. Al-Charrakh; JawadK.Al-Khafaj

karbala journal of pharmaceutical sciences, Volume 4, Issue 4, Pages 91-102

Out of 301 clinical samples, a total of 46 (15.2%) Staphylococcus aureus isolates were recovered, of which (84.7) were isolated from skin samples, (13%) from both ear and urine, and (2.1%) from sputum.44 (95%) isolates were identified as β-lactam resistant. Out of these isolates, 32(72%) were found in skin samples. All 44 β-lactam resistant isolates were subjected to disk diffusion test (DDT) for detectionthe susceptibility to 17 antibiotics used in the present study. The study showed that S. aureus isolates were resistant to most β-lactam antibiotics, but they were sensitive to imipenem, meropenem and rifampin.The susceptibility tovancomycin was tested using Two-fold agar dilution method. 33(75%) of S. aureus isolates showed sensitivity to vancomycin while 11(25%) showed reduced susceptibility to vancomycin and were identified as Vancomycin intermediate resistant S. aureus (VISA). Out of 44 β-lactam resistant isolates 13(29.5%) isolates were found to be resistant to oxacillin and identified as MRSA as they were resistant to both oxacillin and cefoxitin.Out of 13 MRSA isolates, three isolates were classified as MDR-MRSA, and ten isolates as NMDR-MRSA. All MDR and NMDR were sensitive to vancomycin.