ISSN: 7027-2221

Keywords : Thrombosis

Activity assay of plasma fibrinogen in patients with diabetes.

Mohammed Shnain Ali

karbala journal of pharmaceutical sciences, Volume 4, Issue 6, Pages 127-131

Thrombosis secondary to atherosclerosis or hypercoagulability state in diabetes mellitus may be the cause of death in many patients. Patients with diabetes mellitus (n=28, 16 males and 12 females), together with 28 age and sex matched healthy individuals (as controls), were studied after their consent. For each individual (patients and controls), following medical history,
4 ml of venous blood sample was obtained and investigated for HbA1c level, fibrinogen level by doing Claus technique and blood sugar estimation. Hyperfibrinogenaemia in patients with diabetes mellitus (mean plasma fibrinogen 6.8±1.1) is statistically significant (P< 0.05) as compared to control (mean plasma fibrinogen 3.3±1.3). Plasma fibrinogen level is high in patients with diabetes mellitus, suggesting that plasma fibrinogen can contribute to vascular diseases in patients with diabetes mellitus like vascular thrombosis.