Author : A. Yass, Iman
Synthesis of substitutead 1,3-Oxazepine and 1,3-Diazepine Via Schiff Bases for Selfamethoxazole drug
karbala journal of pharmaceutical sciences,
Volume 1, Issue 1, Pages 49-58
Some of aldehydeamino-N-5-methyl-3-oxazolylbenzensulfonamide (Schiff bases) were prepared by condensation of Selfamethoxazole Drug with many substituted aldehydes. These Schiff bases were found to react with maleic anhydride,to give 1,3-Oxazepine-1,3-dione derivatives were react with primary aromatic amines to give the corresponding 1,3-Diazepine-4,7-dione.