karbala journal of pharmaceutical sciences

This study was performed on (35) serum specimen of patients having type 2 diabetes in addition , (40) normal specimens were investigated as control group . The activity of (AST) in diabetic patients was reached to (75.2 ± 11.7) IU/L as compared with normals (19.9 ± 6.1) IU/L . Purification of (AST) from sera of diabetic patients was performed by dialysis and gel filteration (Sephadex G 25) the results of study reveal that Aspartate aminotransferase (AST) activity of type 2 diabetes patient's serum show ahigh significant increase (p< 0.001) compare to normal subject.