Author : K. Jassim, Wissam
Preparation and characterization of some new heterocyclic compounds with evaluating of its biological activity
karbala journal of pharmaceutical sciences,
Volume 2, Issue 2, Pages 241-256
A series of compounds of p-Nitro ethyl benzoate ,p-Nitro benzoic hydrazide , 1-phenyl-4-(p-nitrophenyl) thiosemicarbazide , 3-mercapto-4-phenyl-5- (p-nitro phenyl)-1,2,4- Triazole, 3-hydrazino -4-phenyl-5- (p-nitro phenyl)-1,2,4- Triazole , 3-( substituted benzylidene hydrazine)-4-phenyl-5- (p-nitro phenyl-2-yl)-1,2,4-triazole  and , 2-(substituted aryl)-3-(p-nitrophenyl)-2-yl)-2,3-dihydro-1,3-oxazpine-4,7-dione. and , 2-(substituted aryl)-3-(p-nitrophenyl)-2-yl-2,3-benzo-1,3-oxazpine-4,7-dione  and , 2-(substituted aryl) –tetrazolo-1-yl)-[(3-hydrazino-4-phenyl)- 5-p-nitrophenyl)1,2,4-triazole ] , 2-substituted aryl-3~-[3-hydrazino—4-phenyl-5-(p-nitrophenyl)1,2,4-triazole]-2-yl-thiazolidin-4-one  and . 2-(substituted aryl) –3-[3-hydrazino—4-phenyl-5-(p-nitrophenyl)1,2,4-triazole]-2-yl-imidazolidin-4-one and  were prepared and the chemical structures of these compounds were characterized by FT-IR , 1H-NMR for some of them Uv/vis spectra , C.H.N analysis ), melting points and the purity was checked. Biological activity of these compounds was evaluated.