ISSN: 7027-2221

Author : K. Jassim, Ibtisam


Synthesis and characterization of some new of thiazolidine ,1,2,4-triazole ,1,3,4-thiadiazole , semicarbazide , oxazoline and a study of their biological activity

Ibtisam K. Jassim; Wissam Kh. Jassim; Salwa Abd ALsatar; Abdulla H.Mohammed

karbala journal of pharmaceutical sciences, Volume 3, Issue 3, Pages 213-222

New compounds of oxalic acid dihydrazide [2], bis –[1-phenyl-4-(formyl) thiosemicarbazide [3], bis [5-(biphenyl)-2-(acid hydrazide )-3-N-phenyl-4-(hydroxyl) thiazolidine [4] , bis –[5-mercapto-3-yl-4-phenyl-1,2,4-triazole [5] , bis –[5-(phenylamino)-2-yl-1,3,4-thiazole ] [6], bis [1-phenyl-4-(formyl) semicarbazide [7], bis –[5-(biphenyl)-2-(acid hydrazide )-3-N-phenyl-2-(hydroxyl)oxazoline [8] and bis –[5-hydroxy-4-phenyl-3-yl-1,2,4-triazole [9] have been synthesized. The structures of these compounds were identified by FT-IR spectra and checked by TLC. Some of these compounds were tested against bacteria , Escherchia coli and Staphococcus aureus