Author : S.M. AlSamarrae, Noumaan
karbala journal of pharmaceutical sciences,
Volume 5, Issue 7, Pages 1-11
Bone marrow becomes increasly important hematopoietic tissue. The stroma of the bone marrow is composed of hematopoietic cords, sinusoids, and collagen fibers. The earliest recognizable of granulocytic lineage is the myeloblast. Myeloblast is an oval cell and its chromatin distributed within the nucleus. The promelocyte is sometime slightly larger that its progenitor. Its cytoplasm contains a variable number of large coarse granules. The metamelocytes become smaller and their nucleus attains a definitive indentation. The band cell has a nuclear indentation with concentrate and course chromatin. The segmented cells are characterized by a multilobulated nucleus showing a densely packed chromatin with some clumping.