ISSN: 7027-2221
Author : فارس السامرائی, خلف
Synthesis and characterization of some new N-mannich bases for clonazepam
karbala journal of pharmaceutical sciences,
Volume 7, Issue 11, Pages 246-255
The N- Mannich bases (1-10) have been synthesized by reaction of clonazepam with
formaldehyde or benzaldehyde and different secondary amines. The N-Mannich bases
were subjected to physicochemical studies like melting point determination, TLC and
yield%. The structures of mannich bases were characterized by IR, 1HNMR and
13CNMR spectroscopy.