Author : Hasim Ali, Fatin
karbala journal of pharmaceutical sciences,
Volume 7, Issue 11, Pages 81-94
FNA is a non-invasive method, whose simplicity and safety justify its use for “selective” surgery
and is considered the “gold standard” in the management of thyroid nodules.
The main aim of FNAC is to identify nodules that require surgery and those benign nodules that
can be observed clinically and decrease the overall thyroidectomy rate in patients with benign
diseases., this study was done to evaluate the diagnostic accuracy of fine needle aspiration
cytology as a pre-operative screening methods, it is a prospective study which includes a total of
100 cases for patients aged 13-64 years presented with goiter during the period Jan. 2013- Jan.
2015 in Al Hussain Teaching Hospital in Kerbala. This study resulted in true negative cases
were 81 (Tn), false negative case was 1 ( Fn), True positive were 13 (Tp), and false positive
were 5 cases (Fp).Sensitivity or true positive rate is 92%, Specificity or true negative rate is
94%, Positive predictive value is 72%, Negative predictive value is 98%, Accuracy rate is
94%. False negative FNA cytology result was found in only one of our patients which is less as
compared to other studies where the values range from 1-16%. False negative cases are
encountered when there are no recognizable diagnostic cells in the smear because of sampling
or processing error. We concluded that FNA is the most recommended diagnostic procedure for
the diagnosis of thyroid lesions except follicular tumor.